DRD3 抗体 (Cytoplasmic Domain)
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Quick Overview for DRD3 抗体 (Cytoplasmic Domain) (ABIN302336)
抗原
See all DRD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cytoplasmic Domain
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特异性
- This antibody detects Dopamine Receptor D3 (DRD3).
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- DRD3 antibody was raised against synthetic peptide from 3rd cytoplasmic domain of human DRD3 / Dopamine Receptor D3.
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应用备注
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Immunohistochemistry on Paraffin Sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- DRD3 (Dopamine Receptor D3 (DRD3))
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别名
- Dopamine D3 Receptor
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背景
- The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.Synonyms: D(3) Dopamine receptor, D3DR, DRD3, Dopamin receptor D3, ETM1, FET1
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基因ID
- 1814
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NCBI登录号
- NP_000787
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UniProt
- P35462
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity
抗原
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