PCBP2 抗体 (AA 1-130)
Quick Overview for PCBP2 抗体 (AA 1-130) (ABIN3023340)
抗原
See all PCBP2 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 1-130
- 
                                            序列
- MDTGVIEGGL NVTLTIRLLM HGKEVGSIIG KKGESVKKMR EESGARINIS EGNCPERIIT LAGPTNAIFK AFAMIIDKLE EDISSSMTNS TAASRPPVTL RLVVPASQCG SLIGKGGCKI KEIRESTGAQ
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            产品特性
- Polyclonal Antibodies
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                                            免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human PCBP2 (NP_001122383.1).
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                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            注意事项
- Avoid freeze / thaw cycles
- 
                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - 
                                            : "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos."    in: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018)         (PubMed).        
 
 
- 
                                            : "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos."    in: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018)         (PubMed).        
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    - PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
- 
                                            别名
- PCBP2
- 
                                            背景
- The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.,PCBP2,HNRNPE2,HNRPE2,hnRNP-E2,Epigenetics & Nuclear Signaling,RNA Binding,PCBP2
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                                            分子量
- 33 kDa/34 kDa/35 kDa/38 kDa
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                                            基因ID
- 5094
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                                            UniProt
- Q15366
 抗原
- 
                    
 
                                     
                                     
                                    