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PCBP2 抗体 (AA 1-130)

This anti-PCBP2 antibody is a Rabbit Polyclonal antibody detecting PCBP2 in WB, IHC, IF. Suitable for Human. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3023340
发货至: 中国

Quick Overview for PCBP2 抗体 (AA 1-130) (ABIN3023340)

抗原

See all PCBP2 抗体
PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

适用

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宿主

  • 39
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克隆类型

  • 35
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多克隆

标记

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This PCBP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-130

    序列

    MDTGVIEGGL NVTLTIRLLM HGKEVGSIIG KKGESVKKMR EESGARINIS EGNCPERIIT LAGPTNAIFK AFAMIIDKLE EDISSSMTNS TAASRPPVTL RLVVPASQCG SLIGKGGCKI KEIRESTGAQ

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human PCBP2 (NP_001122383.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Wu, Lou, Ge, Xiong: "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos." in: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018) (PubMed).

  • 抗原

    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

    别名

    PCBP2

    背景

    The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.,PCBP2,HNRNPE2,HNRPE2,hnRNP-E2,Epigenetics & Nuclear Signaling,RNA Binding,PCBP2

    分子量

    33 kDa/34 kDa/35 kDa/38 kDa

    基因ID

    5094

    UniProt

    Q15366
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