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RAPGEF3 抗体 (AA 1-200)

This anti-RAPGEF3 antibody is a 兔 多克隆 antibody detecting RAPGEF3 in WB. Suitable for 人.
产品编号 ABIN3023196
发货至: 中国

Quick Overview for RAPGEF3 抗体 (AA 1-200) (ABIN3023196)

抗原

See all RAPGEF3 抗体
RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAPGEF3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-200

    序列

    MVLRRMHRPR SCSYQLLLEH QRPSCIQGLR WTPLTNSEES LDFSESLEQA STERVLRAGR QLHRHLLATC PNLIRDRKYH LRLYRQCCSG RELVDGILAL GLGVHSRSQV VGICQVLLDE GALCHVKHDW AFQDRDAQFY RFPGPEPEPV GTHEMEEELA EAVALLSQRG PDALLTVALR KPPGQRTDEE LDLIFEELLH

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Epac1/Epac1/RAPGEF3 (NP_001092002.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))

    别名

    RAPGEF3

    背景

    Guanine nucleotide exchange factor (GEF for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.,RAPGEF3,CAMP-GEFI,EPAC,EPAC1,HSU79275,bcm910,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,RAPGEF3

    分子量

    66 kDa/99 kDa/103 kDa

    基因ID

    10411

    UniProt

    O95398

    途径

    cAMP Metabolic Process
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