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HDAC3 抗体 (AA 299-428)

Name: HDAC3 抗体 (AA 299-428)
Brand: antibodies-online
SKU: ABIN3023018
Availability: OutOfStock

This anti-HDAC3 antibody is a 兔多克隆 antibody detecting HDAC3 in WB, IHC, IF, IP 和 ChIP. Suitable for 人. This Primary Antibody has been cited in 3+ publications.

Western blot analysis of extracts of various cell lines, using HDAC3 antibody. (HDAC3 抗体 (AA 299-428))

Immunohistochemistry of paraffin-embedded human esophagus using HDAC3 Antibody. (HDAC3 抗体 (AA 299-428))

IHC (p)

Immunohistochemistry of paraffin-embedded human esophageal cancer using HDAC3 Antibody. (HDAC3 抗体 (AA 299-428))

IHC (p)

Immunohistochemistry of paraffin-embedded mouse brain using HDAC3 Antibody. (HDAC3 抗体 (AA 299-428))

IHC (p)

Immunofluorescence analysis of MCF-7 cells using HDAC3 antibody. (HDAC3 抗体 (AA 299-428))

Immunoprecipitation analysis of 200ug extracts of 293T cells using 1ug HDAC3 antibody. (HDAC3 抗体 (AA 299-428))

Chromatin immunoprecipitation of extracts of 293T cell line, using HDAC3 antibody. (HDAC3 抗体 (AA 299-428))

ChIP

Immunohistochemistry of paraffin-embedded rat brain using HDAC3 Antibody. (HDAC3 抗体 (AA 299-428))

IHC (p)

9 images

(3 references)

产品编号 ABIN3023018

发货至: 中国

Quick Overview for HDAC3 抗体 (AA 299-428) (ABIN3023018)

抗原

See all HDAC3 抗体

HDAC3 (Histone Deacetylase 3 (HDAC3))

适用

人

宿主

兔

克隆类型

多克隆

标记

This HDAC3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

抗原表位
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1

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1
AA 299-428

序列

TVRNVARCWT YETSLLVEEA ISEELPYSEY FEYFAPDFTL HPDVSTRIEN QNSRQYLDQI RQTIFENLKM LNHAPSVQIH DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 299-428 of human HDAC3 (NP_003874.2).

亚型

IgG
anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibody
HDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) (pSer424) antibody
HDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibody
HDAC3 适用: 人 WB, ELISA, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 319-428) antibody
HDAC3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A3 unconjugated

anti-Histone Deacetylase 3 (HDAC3) antibody
HDAC3 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) (C-Term) antibody
HDAC3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 1-428) antibody
HDAC3 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 2F9-4B7 unconjugated

anti-Histone Deacetylase 3 (HDAC3) (AA 31-130) antibody
HDAC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 3 (HDAC3) antibody
HDAC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 4D4 unconjugated Recombinant Antibody

anti-Histone Deacetylase 3 (HDAC3) (AA 224-428) antibody
HDAC3 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7G6C5 unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:20 - 1:100

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Fan, Li, Wang, Emerson, Xu: "A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer." in: Cancers, Vol. 13, Issue 15, (2021) (PubMed).

Wei, Liu, Chen, Gao, Lu, Zhang, Ding, Wang, Chen, Shi, Li, Yu, Wong: "Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription." in: Cell research, Vol. 27, Issue 7, pp. 898-915, (2018) (PubMed).

Liu, Lu, Zhang, Zhang, Lu, Xie, Cheng, Shen, Zhang: "C/EBPα negatively regulates SIRT7 expression via recruiting HDAC3 to the upstream-promoter of hepatocellular carcinoma cells." in: Biochimica et biophysica acta, Vol. 1859, Issue 2, pp. 348-54, (2016) (PubMed).
抗原

HDAC3 (Histone Deacetylase 3 (HDAC3))

别名

HDAC3

背景

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.,HD3,RPD3,RPD3-2,HDAC3,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,G1/S Checkpoint,Notch Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,NF-kB Signaling Pathway,Stem Cells,Cardiovascular,Heart,Hypertrophy,Lipids,HDAC3

分子量

48 kDa/49 kDa

基因ID

8841

UniProt

O15379

途径

Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development