DNMT3A 抗体 (AA 500-700)
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北京 101111
Quick Overview for DNMT3A 抗体 (AA 500-700) (ABIN3022834)
抗原
See all DNMT3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 500-700
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序列
- SVTQKHIQEW GPFDLVIGGS PCNDLSIVNP ARKGLYEGTG RLFFEFYRLL HDARPKEGDD RPFFWLFENV VAMGVSDKRD ISRFLESNPV MIDAKEVSAA HRARYFWGNL PGMNRPLAST VNDKLELQEC LEHGRIAKFS KVRTITTRSN SIKQGKDQHF PVFMNEKEDI LWCTEMERVF GFPVHYTDVS NMSRLARQRL L
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human DNMT3A (NP_715640.2).
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亚型
- IgG
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anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibody
DNMT3A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01852 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 26-100) antibodyDNMT3A 适用: 人, 小鼠, 大鼠 FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 46-180) antibodyDNMT3A 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4G5F11 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (2meLys44) antibodyDNMT3A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibodyDNMT3A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 1-912) antibodyDNMT3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 680-902) antibodyDNMT3A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) antibodyKO Validated DNMT3A 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) antibodyDNMT3A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2230 unconjugated Recombinant Antibody
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) antibodyDNMT3A 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB7245 unconjugated
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应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).
: "Anticancer drugs induce hypomethylation of the acetylcholinesterase promoter via a phosphorylated-p38-DNMT1-AChE pathway in apoptotic hepatocellular carcinoma cells." in: The international journal of biochemistry & cell biology, Vol. 68, pp. 21-32, (2016) (PubMed).
: "Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells." in: Neuroscience, Vol. 294, pp. 172-81, (2015) (PubMed).
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: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).
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- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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别名
- DNMT3A
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背景
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.,DNMT3A,DNMT3A2,M.HsaIIIA,TBRS,DNMT3A,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,DNA methylation,DNMT3A
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分子量
- 16 kDa/81 kDa/101 kDa
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基因ID
- 1788
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UniProt
- Q9Y6K1
抗原
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