Cyclin B1 抗体 (C-Term)
Quick Overview for Cyclin B1 抗体 (C-Term) (ABIN3022807)
抗原
See all Cyclin B1 (CCNB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- TMLDYDMVHF PPSQIAAGAF CLALKILDNG EWTPTLQHYL SYTEESLLPV MQHLAKNVVM VNQGLTKHMT VKNKYATSKH AKISTLPQLN SALVQDLAKA VAKV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 330 to the C-terminus of human Cyclin B1 (NP_114172.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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A novel HDAC6 inhibitor exerts an anti-cancer effect by triggering cell cycle arrest and apoptosis in gastric cancer." in: European journal of pharmacology, Vol. 828, pp. 67-79, (2018) (PubMed).
: "Antitumor activity of the microtubule inhibitor MBRI-001 against human hepatocellular carcinoma as monotherapy or in combination with sorafenib." in: Cancer chemotherapy and pharmacology, Vol. 81, Issue 5, pp. 853-862, (2018) (PubMed).
: "Prevention of Simvastatin-Induced Inhibition of Tendon Cell Proliferation and Cell Cycle Progression by Geranylgeranyl Pyrophosphate." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 149, Issue 2, pp. 326-34, (2016) (PubMed).
: "Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation." in: Nature communications, Vol. 6, pp. 7023, (2015) (PubMed).
: "Platelet-rich plasma increases proliferation of tendon cells by modulating Stat3 and p27 to up-regulate expression of cyclins and cyclin-dependent kinases." in: Cell proliferation, Vol. 48, Issue 4, pp. 413-20, (2015) (PubMed).
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A novel HDAC6 inhibitor exerts an anti-cancer effect by triggering cell cycle arrest and apoptosis in gastric cancer." in: European journal of pharmacology, Vol. 828, pp. 67-79, (2018) (PubMed).
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- Cyclin B1 (CCNB1)
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别名
- CCNB1
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背景
- The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.,CCNB,CCNB1,Cyclin B1,cyclin B1,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,G2/M DNA Damage Checkpoint,Endocrine & Metabolism,AMPK Signaling Pathway,CCNB1
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分子量
- 44 kDa/48 kDa
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基因ID
- 891
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UniProt
- P14635
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途径
- Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
抗原
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