beta 2 Adrenergic Receptor 抗体 (AA 334-413)
Quick Overview for beta 2 Adrenergic Receptor 抗体 (AA 334-413) (ABIN3022784)
抗原
See all beta 2 Adrenergic Receptor (ADRB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 334-413
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序列
- IAFQELLCLR RSSLKAYGNG YSSNGNTGEQ SGYHVEQEKE NKLLCEDLPG TEDFVGHQGT VPSDNIDSQG RNCSTNDSLL
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 334-413 of human ADRB2 (NP_000015.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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别名
- ADRB2
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背景
- This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.,ADRB2,ADRB2R,ADRBR,B2AR,BAR,BETA2AR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cardiovascular,Heart,Cardiogenesis,ADRB2
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分子量
- 46 kDa
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基因ID
- 154
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UniProt
- P07550
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途径
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
抗原
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