Prosaposin 抗体 (AA 60-310)
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北京 101111
Quick Overview for Prosaposin 抗体 (AA 60-310) (ABIN3022606)
抗原
See all Prosaposin (PSAP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-310
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序列
- SLPCDICKDV VTAAGDMLKD NATEEEILVY LEKTCDWLPK PNMSASCKEI VDSYLPVILD IIKGEMSRPG EVCSALNLCE SLQKHLAELN HQKQLESNKI PELDMTEVVA PFMANIPLLL YPQDGPRSKP QPKDNGDVCQ DCIQMVTDIQ TAVRTNSTFV QALVEHVKEE CDRLGPGMAD ICKNYISQYS EIAIQMMMHM QPKEICALVG FCDEVKEMPM QTLVPAKVAS KNVIPALELV EPIKKHEVPA K
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 60-310 of human PSAP (NP_002769.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Prosaposin (PSAP)
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别名
- PSAP
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背景
- This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,PSAP,GLBA,SAP1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,PSAP
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分子量
- 58 kDa
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基因ID
- 5660
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UniProt
- P07602
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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