IL-25 抗体 (AA 115-132)
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Quick Overview for IL-25 抗体 (AA 115-132) (ABIN302245)
抗原
See all IL-25 (IL25) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 115-132
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特异性
- This antibody detects Interleukin 17E (IL17E) (IL25).
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交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
产品特性
- Synonyms: IL-25, IL17E, IL-17E, Interleukin-17E
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纯化方法
- Protein G Chromatography.
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免疫原
- A synthetic peptide of amino acids 115-132, obtained from the human IL-17E proteinsequence.
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亚型
- IgG1
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anti-Interleukin 25 (IL25) (AA 32-148) antibody
IL25 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 25 (IL25) (Internal Region) antibodyIL25 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 25 (IL25) (AA 33-169) antibodyIL25 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 25 (IL25) antibody (Biotin)IL25 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 11K8B1 Biotin
anti-Interleukin 25 (IL25) (AA 76-104) antibodyIL25 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 25 (IL25) (AA 1-177) antibodyIL25 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 25 (IL25) antibody (PE)IL25 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal PE
anti-Interleukin 25 (IL25) (AA 115-132) antibodyIL25 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Interleukin 25 (IL25) (AA 33-177) antibodyIL25 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot (2 μg/mL). Immunohistochemistry on Paraffin Sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or(in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- IL-25 (IL25) (Interleukin 25 (IL25))
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别名
- Interleukin-25 / IL25
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背景
- Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated by Shi, et al and Lee, et al. and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8. Exposure of mice to IL17 resulted in a Th-2 like response characterized by increased serum IgE, IgG1 and IgA levels, blood eosinophilia, increased lymphocytes and neutrophils, and pathological changes in the tissues that included eosinophilic infiltrates, increased mucus production, B-lymphocyte hyperplasia and epithelial cell hyperplasia/hypertrophy.Synonyms: IL-17E, IL-25, IL17E, Interleukin-17E
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基因ID
- 64806
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UniProt
- Q9H293
抗原
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