Glucose-6-Phosphate Dehydrogenase 抗体 (AA 246-545)
Our Local Distributor
北京 101111
Quick Overview for Glucose-6-Phosphate Dehydrogenase 抗体 (AA 246-545) (ABIN3022095)
抗原
See all Glucose-6-Phosphate Dehydrogenase (G6PD) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 246-545
-
序列
- FANRIFGPIW NRDNIACVIL TFKEPFGTEG RGGYFDEFGI IRDVMQNHLL QMLCLVAMEK PASTNSDDVR DEKVKVLKCI SEVQANNVVL GQYVGNPDGE GEATKGYLDD PTVPRGSTTA TFAAVVLYVE NERWDGVPFI LRCGKALNER KAEVRLQFHD VAGDIFHQQC KRNELVIRVQ PNEAVYTKMM TKKPGMFFNP EESELDLTYG NRYKNVKLPD AYERLILDVF CGSQMHFVRS DELREAWRIF TPLLHQIELE KPKPIPYIYG SRGPTEADEL MKRVGFQYEG TYKWVNPHKL
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 246-545 of human G6PD (NP_000393.4).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid freeze / thaw cycles
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
-
: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
: "Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." in: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).
-
: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
-
- Glucose-6-Phosphate Dehydrogenase (G6PD)
-
别名
- G6PD
-
背景
- This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.,G6PD,G6PD1,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Heart,Cardiac metabolism,Cardiovascular diseases,Heart disease,G6PD
-
分子量
- 59 kDa/62 kDa/63 kDa
-
基因ID
- 2539
-
UniProt
- P11413
-
途径
- Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
-