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UCP3 抗体 (AA 1-110)

This anti-UCP3 antibody is a 兔 多克隆 antibody detecting UCP3 in WB. Suitable for 人.
产品编号 ABIN3022086
发货至: 中国

Quick Overview for UCP3 抗体 (AA 1-110) (ABIN3022086)

抗原

See all UCP3 抗体
UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

适用

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宿主

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克隆类型

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多克隆

标记

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This UCP3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-110

    序列

    MVGLKPSDVP PTMAVKFLGA GTAACFADLV TFPLDTAKVR LQIQGENQAV QTARLVQYRG VLGTILTMVR TEGPCSPYNG LVAGLQRQMS FASIRIGLYD SVKQVYTPKG

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human UCP3 (NP_073714.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))

    别名

    UCP3

    背景

    Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression, this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.,UCP3,SLC25A9,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Cardiovascular,Hypoxia,Lipids,Fatty Acids,UCP3

    分子量

    22 kDa/29 kDa/34 kDa

    基因ID

    7352

    UniProt

    P55916

    途径

    Proton Transport
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