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Coagulation Factor X 抗体 (AA 235-488)

This anti-Coagulation Factor X antibody is a 兔 多克隆 antibody detecting Coagulation Factor X in WB 和 IF. Suitable for 人.
产品编号 ABIN3021978
发货至: 中国

Quick Overview for Coagulation Factor X 抗体 (AA 235-488) (ABIN3021978)

抗原

See all Coagulation Factor X (F10) 抗体
Coagulation Factor X (F10)

适用

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宿主

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  • 1

克隆类型

  • 71
  • 16
多克隆

标记

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This Coagulation Factor X antibody is un-conjugated

应用范围

  • 50
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 235-488

    序列

    IVGGQECKDG ECPWQALLIN EENEGFCGGT ILSEFYILTA AHCLYQAKRF KVRVGDRNTE QEEGGEAVHE VEVVIKHNRF TKETYDFDIA VLRLKTPITF RMNVAPACLP ERDWAESTLM TQKTGIVSGF GRTHEKGRQS TRLKMLEVPY VDRNSCKLSS SFIITQNMFC AGYDTKQEDA CQGDSGGPHV TRFKDTYFVT GIVSWGEGCA RKGKYGIYTK VTAFLKWIDR SMKTRGLPKA KSHAPEVITS SPLK

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 235-488 of human F10 (NP_000495.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:10 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Coagulation Factor X (F10)

    别名

    F10

    背景

    This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.,F10,FX,FXA,Cardiovascular,Blood,Coagulation,F10

    分子量

    54 kDa

    基因ID

    2159

    UniProt

    P00742
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