Fibrinogen beta Chain 抗体 (AA 202-491)
Quick Overview for Fibrinogen beta Chain 抗体 (AA 202-491) (ABIN3021950)
抗原
See all Fibrinogen beta Chain (FGB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 202-491
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序列
- LENLRSKIQK LESDVSAQME YCRTPCTVSC NIPVVSGKEC EEIIRKGGET SEMYLIQPDS SVKPYRVYCD MNTENGGWTV IQNRQDGSVD FGRKWDPYKQ GFGNVATNTD GKNYCGLPGE YWLGNDKISQ LTRMGPTELL IEMEDWKGDK VKAHYGGFTV QNEANKYQIS VNKYRGTAGN ALMDGASQLM GENRTMTIHN GMFFSTYDRD NDGWLTSDPR KQCSKEDGGG WWYNRCHAAN PNGRYYWGGQ YTWDMAKHGT DDGVVWMNWK GSWYSMRKMS MKIRPFFPQQ
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 202-491 of human FGB (NP_005132.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Fibrinogen beta Chain (FGB)
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别名
- FGB
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背景
- The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FGB,HEL-S-78p,Cardiovascular,Blood,Coagulation,FGB
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分子量
- 55 kDa
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基因ID
- 2244
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UniProt
- P02675
抗原
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