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ERG 抗体 (AA 1-280)

This anti-ERG antibody is a 兔 多克隆 antibody detecting ERG in WB. Suitable for 人.
产品编号 ABIN3021820
发货至: 中国

Quick Overview for ERG 抗体 (AA 1-280) (ABIN3021820)

抗原

See all ERG 抗体
ERG (ERG, ETS transcription factor (ERG))

适用

  • 60
  • 35
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  • 1
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宿主

  • 51
  • 9
  • 1

克隆类型

  • 42
  • 19
多克隆

标记

  • 38
  • 5
  • 4
  • 2
  • 2
  • 2
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This ERG antibody is un-conjugated

应用范围

  • 35
  • 22
  • 17
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  • 11
  • 8
  • 6
  • 3
  • 1
  • 1
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 9
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    • 5
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    • 1
    • 1
    • 1
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    AA 1-280

    序列

    MASTIKEALS VVSEDQSLFE CAYGTPHLAK TEMTASSSSD YGQTSKMSPR VPQQDWLSQP PARVTIKMEC NPSQVNGSRN SPDECSVAKG GKMVGSPDTV GMNYGSYMEE KHMPPPNMTT NERRVIVPAD PTLWSTDHVR QWLEWAVKEY GLPDVNILLF QNIDGKELCK MTKDDFQRLT PSYNADILLS HLHYLRETPL PHLTSDDVDK ALQNSPRLMH ARNTGGAAFI FPNTSVYPEA TQRITTRPDL PYEPPRRSAW TGHGHPTPQS KAAQPSPSTV

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ERG (NP_891548.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ERG (ERG, ETS transcription factor (ERG))

    别名

    ERG

    背景

    This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined.,ERG,erg-3,p55,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Stem Cells,Hematopoietic Progenitors,ERG

    分子量

    35 kDa/36 kDa/41 kDa/52 kDa/53 kDa/54 kDa

    基因ID

    2078

    UniProt

    P11308
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