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RASSF1 抗体 (AA 101-340)

This anti-RASSF1 antibody is a 兔 多克隆 antibody detecting RASSF1 in WB. Suitable for 人.
产品编号 ABIN3021712
发货至: 中国

Quick Overview for RASSF1 抗体 (AA 101-340) (ABIN3021712)

抗原

See all RASSF1 抗体
RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This RASSF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 101-340

    序列

    CCGPRDLGWE PAVERDTNVD EPVEWETPDL SQAEIEQKIK EYNAQINSNL FMSLNKDGSY TGFIKVQLKL VRPVSVPSSK KPPSLQDARR GPGRGTSVRR RTSFYLPKDA VKHLHVLSRT RAREVIEALL RKFLVVDDPR KFALFERAER HGQVYLRKLL DDEQPLRLRL LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL QKYSYCRQKI QEALHACPLG

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 101-340 of human RASSF1 (NP_009113.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

    别名

    RASSF1

    背景

    This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,RASSF1,123F2,NORE2A,RASSF1A,RDA32,REH3P21,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,RASSF1

    分子量

    8 kDa/9 kDa/16 kDa/21 kDa/31 kDa/38 kDa/39 kDa

    基因ID

    11186

    UniProt

    Q9NS23
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