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MMP3 抗体 (AA 248-477)

This anti-MMP3 antibody is a 兔 多克隆 antibody detecting MMP3 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3021709
发货至: 中国

Quick Overview for MMP3 抗体 (AA 248-477) (ABIN3021709)

抗原

See all MMP3 抗体
MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

适用

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宿主

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克隆类型

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多克隆

标记

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This MMP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 248-477

    序列

    RFRLSQDDIN GIQSLYGPPP DSPETPLVPT EPVPPEPGTP ANCDPALSFD AVSTLRGEIL IFKDRHFWRK SLRKLEPELH LISSFWPSLP SGVDAAYEVT SKDLVFIFKG NQFWAIRGNE VRAGYPRGIH TLGFPPTVRK IDAAISDKEK NKTYFFVEDK YWRFDEKRNS MEPGFPKQIA EDFPGIDSKI DAVFEEFGFF YFFTGSSQLE FDPNAKKVTH TLKSNSWLNC

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 248-477 of human MMP3 (NP_002413.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Xia, Zhang, Ge: "C/EBP? Mediates TNF-?-Induced Cancer Cell Migration by Inducing MMP Expression Dependent on p38 MAPK." in: Journal of cellular biochemistry, (2015) (PubMed).

  • 抗原

    MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

    别名

    MMP3

    背景

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.,MMP3,CHDS6,MMP-3,SL-1,STMY,STMY1,STR1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP3

    分子量

    53 kDa

    基因ID

    4314

    UniProt

    P08254
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