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TTR 抗体 (AA 21-147)

Cited in 1 publication. This 兔 多克隆 anti-TTR antibody specifically detects TTR in WB, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN3021474
发货至: 中国
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Quick Overview for TTR 抗体 (AA 21-147) (ABIN3021474)

抗原

See all TTR 抗体
TTR (Transthyretin (TTR))

适用

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宿主

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克隆类型

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多克隆

标记

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This TTR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 21-147

    序列

    GPTGTGESKC PLMVKVLDAV RGSPAINVAV HVFRKAADDT WEPFASGKTS ESGELHGLTT EEEFVEGIYK VEIDTKSYWK ALGISPFHEH AEVVFTANDS GPRRYTIAAL LSPYSYSTTA VVTNPKE

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_000362.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Tesch, Abdirama, Grießbach, Brand, Goerlich, Humrich, Bacher, Hiepe, Riemekasten, Enghard: "Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods." in: Scientific reports, Vol. 10, Issue 1, pp. 21312, (2020) (PubMed).

  • 抗原

    TTR (Transthyretin (TTR))

    别名

    TTR

    背景

    This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.,TTR,CTS,CTS1,HEL111,HsT2651,PALB,TBPA,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Blood,Serum Proteins,TTR

    分子量

    15 kDa

    基因ID

    7276

    UniProt

    P02766

    途径

    Hormone Transport
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