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SMAD1 抗体 (AA 20-240)

Name: SMAD1 抗体 (AA 20-240)
Brand: antibodies-online
SKU: ABIN3021439
Availability: OutOfStock

This anti-SMAD1 antibody is a 兔多克隆 antibody detecting SMAD1 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.

Western blot analysis of extracts of various cell lines,using SMAD1 antibody. (SMAD1 抗体 (AA 20-240))

Immunofluorescence (IF) image for anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-240) antibody (ABIN3021439) (SMAD1 抗体 (AA 20-240))

Immunohistochemistry of paraffin-embedded rat brain using SMAD1 antibody. (SMAD1 抗体 (AA 20-240))

IHC (p)

Immunohistochemistry of paraffin-embedded human kidney using SMAD1 antibody. (SMAD1 抗体 (AA 20-240))

IHC (p)

Immunofluorescence analysis of HeLa cells using SMAD1 antibody. (SMAD1 抗体 (AA 20-240))

7 images

(1 reference)

产品编号 ABIN3021439

发货至: 中国

Quick Overview for SMAD1 抗体 (AA 20-240) (ABIN3021439)

抗原

See all SMAD1 抗体

SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This SMAD1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

抗原表位
27

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15

9

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AA 20-240

序列

WKQGDEEEKW AEKAVDALVK KLKKKKGAME ELEKALSCPG QPSNCVTIPR SLDGRLQVSH RKGLPHVIYC RVWRWPDLQS HHELKPLECC EFPFGSKQKE VCINPYHYKR VESPVLPPVL VPRHSEYNPQ HSLLAQFRNL GQNEPHMPLN ATFPDSFQQP NSHPFPHSPN SSYPNSPGSS SSTYPHSPTS SDPGSPFQMP ADTPPPAYLP PEDPMTQDGS Q

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human Smad1 (NP_001003688.1).

亚型

IgG
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibody
SMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-110) antibody
SMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D3 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibody
SMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2A1 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 202-335) antibody
SMAD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer187) antibody
SMAD1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibody
SMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-330) antibody
SMAD1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1356CT119-18-55 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibody
SMAD1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB43846 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer465) antibody
SMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibody
SMAD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A1 unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Kong, Liang, Chen, Yang, Liu, Li, Feng, Wu, Liu, Tang, Yu, Ou, Lu, Yan: "Hyaluronan negatively regulates vascular calcification involving BMP2 signaling." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 98, Issue 10, pp. 1320-1332, (2018) (PubMed).
抗原

SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

别名

SMAD1

背景

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.,BSP-1,BSP1,JV4-1,JV41,MADH1,MADR1,Smad1,SMAD1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Stem Cells,SMADs,SMAD1

分子量

15 kDa/52 kDa

基因ID

4086

UniProt

Q15797

途径

Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development