FAM3B 抗体 (AA 30-235)
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北京 101111
Quick Overview for FAM3B 抗体 (AA 30-235) (ABIN3021391)
抗原
See all FAM3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-235
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序列
- ELIPDAPLSS AAYSIRSIGE RPVLKAPVPK RQKCDHWTPC PSDTYAYRLL SGGGRSKYAK ICFEDNLLMG EQLGNVARGI NIAIVNYVTG NVTATRCFDM YEGDNSGPMT KFIQSAAPKS LLFMVTYDDG STRLNNDAKN AIEALGSKEI RNMKFRSSWV FIAAKGLELP SEIQREKINH SDAKNNRYSG WPAEIQIEGC IPKERS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3).
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亚型
- IgG
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anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 1-235) antibody
FAM3B 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 1-100) antibodyFAM3B 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 31-235) antibodyFAM3B 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (C-Term) antibodyFAM3B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 1-235) antibodyFAM3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 24-51), (N-Term) antibodyFAM3B 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21063 unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 30-235) antibodyFAM3B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) antibodyFAM3B 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) antibodyFAM3B 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 3, Member B (FAM3B) (AA 1-235) antibodyFAM3B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- IHC,1:100 - 1:200,IF,1:100 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FAM3B (Family with Sequence Similarity 3, Member B (FAM3B))
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别名
- FAM3B
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背景
- FAM3B, also known as Pancreatic-derived factor (PANDER), is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B can induce apoptosis of alpha and beta cells in a dose- and time-dependent manner. Previous studies showed that FAM3B regulates glucose and lipid metabolism through interaction with liver and endocrine pancreas. FAM3B silencing activates both extrinsic and intrinsic apoptotic pathways. In general, silencing FAM3B promoted p53 phosphorylation and induced p53 accumulation by decreasing Mdm2 expression, which resulted in apoptotic cell death.,FAM3B,2-21,C21orf11,C21orf76,ORF9,PANDER,PRED44,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,FAM3B
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分子量
- 20 kDa/25 kDa/30 kDa
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基因ID
- 54097
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UniProt
- P58499
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途径
- Hormone Transport
抗原
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