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Calreticulin 抗体

This anti-Calreticulin antibody is a 兔 多克隆 antibody detecting Calreticulin in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3021344
发货至: 中国

Quick Overview for Calreticulin 抗体 (ABIN3021344)

抗原

See all Calreticulin (CALR) 抗体
Calreticulin (CALR)

适用

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人, 小鼠, 大鼠

宿主

  • 137
  • 25
  • 2
  • 1

克隆类型

  • 126
  • 39
多克隆

标记

  • 97
  • 13
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  • 2
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This Calreticulin antibody is un-conjugated

应用范围

  • 134
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  • 3
  • 2
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human CALR

    亚型

    IgG
  • 应用备注

    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C/-80 °C
  • 抗原

    Calreticulin (CALR)

    别名

    CALR

    背景

    Calcium is a universal signaling molecule involved in many cellular functions such as cell motility, metabolism, protein modification, protein folding and apoptosis. Calcium is stored in the endoplasmic reticulum (ER), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP3 Receptor. Calreticulin also functions as an ER chaperone that ensures proper folding and quality control of newly synthesized glycoproteins. As such, calreticulin presumably does not alter protein folding but ensures proper timing for efficient folding and subunit assembly. Furthermore, calreticulin retains proteins in non-native conformation within the ER and targets them for degradation.
    Synonyms: CALR, CRT, FLJ26680, RO, SSA, cC1qR

    基因ID

    811

    UniProt

    P27797

    途径

    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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