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Hexokinase 2 抗体 (AA 1-120)

This anti-Hexokinase 2 antibody is a 兔 多克隆 antibody detecting Hexokinase 2 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3021256
发货至: 中国

Quick Overview for Hexokinase 2 抗体 (AA 1-120) (ABIN3021256)

抗原

See all Hexokinase 2 (HK2) 抗体
Hexokinase 2 (HK2)

适用

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宿主

  • 76
  • 22

克隆类型

  • 74
  • 24
多克隆

标记

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This Hexokinase 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 11
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    • 3
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    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 1-120

    序列

    MIASHLLAYF FTELNHDQVQ KVDQYLYHMR LSDETLLEIS KRFRKEMEKG LGATTHPTAA VKMLPTFVRS TPDGTEHGEF LALDLGGTNF RVLWVKVTDN GLQKVEMENQ IYAIPEDIMR

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Hexokinase II (NP_000180.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Guo, Yao, Zhan, Hu, Yue, Cheng, Liu, Ye, Qing, Zhang, Liu: "N-methylhemeanthidine chloride, a novel Amaryllidaceae alkaloid, inhibits pancreatic cancer cell proliferation via down-regulating AKT activation." in: Toxicology and applied pharmacology, Vol. 280, Issue 3, pp. 475-83, (2014) (PubMed).

  • 抗原

    Hexokinase 2 (HK2)

    别名

    HK2

    背景

    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.,HK2,HKII,HXK2,hexokinase-2,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,Cardiovascular,Heart,Cardiac metabolism,HK2

    分子量

    102 kDa

    基因ID

    3099

    UniProt

    P52789

    途径

    PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
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