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WASP 抗体 (AA 60-250)

This anti-WASP antibody is a 兔 多克隆 antibody detecting WASP in WB. Suitable for 人.
产品编号 ABIN3021208
发货至: 中国

Quick Overview for WASP 抗体 (AA 60-250) (ABIN3021208)

抗原

See all WASP (WAS) 抗体
WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

适用

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宿主

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克隆类型

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多克隆

标记

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This WASP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 60-250

    序列

    GAEHWTKEHC GAVCFVKDNP QKSYFIRLYG LQAGRLLWEQ ELYSQLVYST PTPFFHTFAG DDCQAGLNFA DEDEAQAFRA LVQEKIQKRN QRQSGDRRQL PPPPTPANEE RRGGLPPLPL HPGGDQGGPP VGPLSLGLAT VDIQNPDITS SRYRGLPAPG PSPADKKRSG KKKISKADIG APSGFKHVSH V

    交叉反应

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 60-250 of human WASPP (NP_000368.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

    别名

    WAS

    背景

    The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.,WAS,IMD2,SCNX,THC,THC1,WASP,WASPA,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Actins,Immunology & Inflammation,T Cell Receptor Signaling Pathway,WAS

    分子量

    52 kDa

    基因ID

    7454

    UniProt

    P42768
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