ITGA4 抗体 (C-Term)
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Quick Overview for ITGA4 抗体 (C-Term) (ABIN3021106)
抗原
See all ITGA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FLCNFGKMES GKEASVHIQL EGRPSILEMD ETSALKFEIR ATGFPEPNPR VIELNKDENV AHVLLEGLHH QRPKRYFTIV IISSSLLLGL IVLLLISYVM WKAGFFKRQY KSILQEENRR DSWSYINSKS NDD
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human Integrin alpha 4 (ITGA4/CD49d) (NP_000876.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ITGA4 (Integrin alpha 4 (ITGA4))
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别名
- ITGA4
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背景
- The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.,ITGA4,CD49D,IA4,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Neural Stem Cells,ITGA4
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分子量
- 21 kDa/114 kDa
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基因ID
- 3676
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UniProt
- P13612
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途径
- Integrin Complex
抗原
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