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P4HB 抗体 (AA 329-508)

This anti-P4HB antibody is a 兔 多克隆 antibody detecting P4HB in WB, IHC, IP 和 IF. Suitable for 人.
产品编号 ABIN3021094
发货至: 中国

Quick Overview for P4HB 抗体 (AA 329-508) (ABIN3021094)

抗原

See all P4HB 抗体
P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

适用

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宿主

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克隆类型

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多克隆

标记

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This P4HB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 抗原表位

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    AA 329-508

    序列

    PESEELTAER ITEFCHRFLE GKIKPHLMSQ ELPEDWDKQP VKVLVGKNFE DVAFDEKKNV FVEFYAPWCG HCKQLAPIWD KLGETYKDHE NIVIAKMDST ANEVEAVKVH SFPTLKFFPA SADRTVIDYN GERTLDGFKK FLESGGQDGA GDDDDLEDLE EAEEPDMEED DDQKAVKDEL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 329-508 of human P4HB (NP_000909.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:20 - 1:100,IP,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

    别名

    P4HB

    背景

    This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.,P4HB,CLCRP1,DSI,ERBA2L,GIT,P4Hbeta,PDI,PDIA1,PHDB,PO4DB,PO4HB,PROHB,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Endocrine & Metabolism,Lipid Metabolism,P4HB

    分子量

    57 kDa

    基因ID

    5034

    UniProt

    P07237

    途径

    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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