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TCL1A 抗体 (AA 1-114)

This anti-TCL1A antibody is a 兔 多克隆 antibody detecting TCL1A in WB. Suitable for 人.
产品编号 ABIN3021014
发货至: 中国
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Quick Overview for TCL1A 抗体 (AA 1-114) (ABIN3021014)

抗原

See all TCL1A 抗体
TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

适用

  • 82
  • 3
  • 2

宿主

  • 51
  • 33
  • 1

克隆类型

  • 51
  • 34
多克隆

标记

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This TCL1A antibody is un-conjugated

应用范围

  • 51
  • 40
  • 28
  • 18
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Western Blotting (WB)
  • 抗原表位

    • 34
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    AA 1-114

    序列

    MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD

    交叉反应

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human TCL1A (NP_001092195.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

    别名

    TCL1A

    背景

    Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010],TCL1A,TCL1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,TCL1A

    分子量

    13 kDa

    基因ID

    8115

    UniProt

    P56279

    途径

    Stem Cell Maintenance
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