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CD69 抗体

CD69 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal FN50 unconjugated
产品编号 ABIN302090
发货至: 中国
  • 抗原 See all CD69 抗体
    CD69
    适用
    • 89
    • 55
    • 14
    • 6
    • 6
    • 6
    • 4
    • 3
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    • 1
    宿主
    • 49
    • 47
    • 19
    • 10
    小鼠
    克隆类型
    • 77
    • 48
    单克隆
    标记
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    This CD69 antibody is un-conjugated
    应用范围
    • 103
    • 47
    • 23
    • 23
    • 14
    • 14
    • 13
    • 13
    • 7
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Anti-Hu CD69 Purified
    特异性
    The mouse monoclonal antibody FN50 recognizes an extracellular epitope of CD69, an lymphocyte early activation marker.
    交叉反应 (详细)
    Human, Other not determined
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Anti-µ-stimulated human B lymphocytes
    克隆位点
    FN50
    亚型
    IgG1
    Top Product
    Discover our top product CD69 Primary Antibody
  • 应用备注
    Flow cytometry: recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Hrdinka, Dráber, Stepánek, Ormsby, Otáhal, Angelisová, Brdicka, Paces, Horejsí, Drbal: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).

    Drbal, Moertelmaier, Holzhauser, Muhammad, Fuertbauer, Howorka, Hinterberger, Stockinger, Schütz: "Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement." in: International immunology, Vol. 19, Issue 5, pp. 675-84, (2007) (PubMed).

    Tomescu, Chehimi, Maino, Montaner: "NK cell lysis of HIV-1-infected autologous CD4 primary T cells: requirement for IFN-mediated NK activation by plasmacytoid dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 4, pp. 2097-104, (2007) (PubMed).

  • 抗原
    CD69
    别名
    CD69 (CD69 产品)
    背景
    CD69 Molecule,CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets, it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.,EA1, AIM, MLR-3, CLEC2C, GP32/28, BL-AC/P26
    基因ID
    969
    UniProt
    Q07108
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