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CDK1 抗体 (AA 208-258)

This anti-CDK1 antibody is a 兔 多克隆 antibody detecting CDK1 in WB, IHC, IF 和 IP. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN3020707
发货至: 中国

Quick Overview for CDK1 抗体 (AA 208-258) (ABIN3020707)

抗原

See all CDK1 抗体
CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

适用

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宿主

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克隆类型

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  • 91
多克隆

标记

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This CDK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 抗原表位

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    AA 208-258

    序列

    SEIDQLFRIF RALGTPNNEV WPEVESLQDY KNTFPKWKPG SLASHVKNLD E

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 208-258 of human CDK1 (NP_001777.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Liu, Fu, Sun, Wang, Geng, Wang, Zou, Bi, Yang et al.: "A New Perspective for Osteosarcoma Therapy: Proteasome Inhibition by MLN9708/2238 Successfully Induces Apoptosis and Cell Cycle Arrest and Attenuates the Invasion Ability of Osteosarcoma Cells in ..." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 2, pp. 451-465, (2017) (PubMed).

    Tsai, Yu, Lin, Cheng, Chen, Pang: "Prevention of Simvastatin-Induced Inhibition of Tendon Cell Proliferation and Cell Cycle Progression by Geranylgeranyl Pyrophosphate." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 149, Issue 2, pp. 326-34, (2016) (PubMed).

  • 抗原

    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

    别名

    CDK1

    背景

    The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CDK1,CDC2,CDC28A,P34CDC2,Epigenetics & Nuclear Signaling,Signal Transduction,G protein signaling,Kinase,Serine/threonine kinases,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,G2/M DNA Damage Checkpoint,Microtubules,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,CDK1

    分子量

    27 kDa/34 kDa

    基因ID

    983

    UniProt

    P06493

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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