CD69 抗体 (FITC)
Quick Overview for CD69 抗体 (FITC) (ABIN302016)
抗原
See all CD69 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
 - Anti-Hu CD69 FITC
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特异性
 - The mouse monoclonal antibody FN50 recognizes an extracellular epitope of CD69, an lymphocyte early activation marker.
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交叉反应 (详细)
 - Human, Other not determined
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纯化方法
 - Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
 - Anti-µ-stimulated human B lymphocytes
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亚型
 - IgG1
 
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应用备注
 - Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
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限制
 - 仅限研究用
 
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溶解方式
 - No reconstitution is necessary.
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缓冲液
 - Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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                        Do not freeze. 
Avoid prolonged exposure to light. - 
                                            
储存条件
 - 4 °C
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储存方法
 - Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
 
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                                            : "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis."    in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011)         (PubMed).        
: "Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement." in: International immunology, Vol. 19, Issue 5, pp. 675-84, (2007) (PubMed).
: "NK cell lysis of HIV-1-infected autologous CD4 primary T cells: requirement for IFN-mediated NK activation by plasmacytoid dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 4, pp. 2097-104, (2007) (PubMed).
 
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                                            : "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis."    in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011)         (PubMed).        
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- CD69
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别名
 - CD69
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背景
 - CD69 Molecule,CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets, it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.,EA1, AIM, MLR-3, CLEC2C, GP32/28, BL-AC/P26
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基因ID
 - 969
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UniProt
 - Q07108
 
抗原
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