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HLA-DP/DR 抗体 (Biotin)

This anti-HLA-DP/DR antibody is a 小鼠 单克隆 antibody detecting HLA-DP/DR in FACS, IP, WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN301998
发货至: 中国

Quick Overview for HLA-DP/DR 抗体 (Biotin) (ABIN301998)

抗原

HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

适用

  • 15
  • 5

宿主

  • 15
小鼠

克隆类型

  • 15
单克隆

标记

  • 4
  • 4
  • 4
  • 2
  • 1
This HLA-DP/DR antibody is conjugated to Biotin

应用范围

  • 15
  • 7
  • 7
  • 4
  • 3
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MEM-136
  • 原理

    Anti-HLA-DR/DP Biotin

    特异性

    The antibody MEM-136 recognizes a common extracellular epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

    免疫原

    PHA-activated peripheral blood lymphocytes.

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.
    Avoid prolonged exposure to light.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: "T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density." in: International immunology, Vol. 11, Issue 5, pp. 777-86, (1999) (PubMed).

  • 抗原

    HLA-DP/DR (MHC Class II HLA-DP/DR (HLA-DP/DR))

    别名

    HLA-DR/DP

    背景

    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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