Cofilin 抗体 (pSer3)
Our Local Distributor
北京 101111
Quick Overview for Cofilin 抗体 (pSer3) (ABIN3019729)
抗原
See all Cofilin (CFL1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer3
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Phosphorylated Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A phospho specific peptide corresponding to residues surrounding S3 of human CFL1
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
-
: "MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis." in: Oncotarget, Vol. 6, Issue 26, pp. 22410-23, (2016) (PubMed).
-
: "MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis." in: Oncotarget, Vol. 6, Issue 26, pp. 22410-23, (2016) (PubMed).
-
- Cofilin (CFL1) (Cofilin 1 (CFL1))
-
别名
- CFL1
-
背景
- The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004],CFL1,CFL,HEL-S-15,cofilin,cofilin-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,Neuroscience,Cell Type Marker,Cardiovascular,Heart,Contractility,Neuron marker,Axon marker,Protein phosphorylation,CFL1
-
分子量
- 18 kDa
-
基因ID
- 1072
-
UniProt
- P23528
-
途径
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
抗原
-