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Cofilin 抗体 (pSer3)

There is 1 publication for this product available. The 兔 多克隆 anti-Cofilin antibody is suitable to detect Cofilin in samples from 人. It has been validated for WB, IHC 和 IF.
产品编号 ABIN3019729
发货至: 中国
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Quick Overview for Cofilin 抗体 (pSer3) (ABIN3019729)

抗原

See all Cofilin (CFL1) 抗体
Cofilin (CFL1) (Cofilin 1 (CFL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Cofilin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pSer3

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding S3 of human CFL1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Hu, Guo, Feng, Zhang, Zhou, Ma, Shen, Tong, Yan, Zhu, Bian, Lai, Deng, Ding: "MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis." in: Oncotarget, Vol. 6, Issue 26, pp. 22410-23, (2016) (PubMed).

  • 抗原

    Cofilin (CFL1) (Cofilin 1 (CFL1))

    别名

    CFL1

    背景

    The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004],CFL1,CFL,HEL-S-15,cofilin,cofilin-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,Neuroscience,Cell Type Marker,Cardiovascular,Heart,Contractility,Neuron marker,Axon marker,Protein phosphorylation,CFL1

    分子量

    18 kDa

    基因ID

    1072

    UniProt

    P23528

    途径

    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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