MYSM1 抗体 (C-Term)
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北京 101111
Quick Overview for MYSM1 抗体 (C-Term) (ABIN3017376)
抗原
See all MYSM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PLPYSQITCL VISEEISPDG SYRLPYKFEV QQMLEEPQWG LVFEKTRWII EKYRLSHSSV PMDKIFRRDS DLTCLQKLLE CMRKTLSKVT NCFMAEEFLT EIENLFLSNY KSNQENGVTE ENCTKELLM
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human MYSM1 (NP_001078956.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
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别名
- MYSM1
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背景
- Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.,MYSM1,2A-DUB,2ADUB,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,MYSM1
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分子量
- 26 kDa/66 kDa/95 kDa
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基因ID
- 114803
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UniProt
- Q5VVJ2
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途径
- Chromatin Binding
抗原
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