GRIN2B 抗体 (C-Term)
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北京 101111
Quick Overview for GRIN2B 抗体 (C-Term) (ABIN3017276)
抗原
See all GRIN2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GSKSYFFRQP TVAGASKARP DFRALVTNKP VVSALHGAVP ARFQKDICIG NQSNPCVPNN KNPRAFNGSS NGHVYEKLSS IESDV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1400 to the C-terminus of human GRIN2B (NP_000825.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
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别名
- GRIN2B
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背景
- N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.,GRIN2B,EIEE27,GluN2B,MRD6,NMDAR2B,NR2B,hNR3,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,GRIN2B
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分子量
- 166 kDa
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基因ID
- 2904
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UniProt
- Q13224
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途径
- Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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