CKMT1B 抗体 (AA 1-85)
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北京 101111
Quick Overview for CKMT1B 抗体 (AA 1-85) (ABIN3017246)
抗原
See all CKMT1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-85
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序列
- MAGPFSRLLS ARPGLRLLAL AGAGSLAAGF LLRPEPVRAA SERRRLYPPS AEYPDLRKHN NCMASHLTPA VYARLCDKTT PTGWT
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human CKMT1B (NP_066270.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
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别名
- CKMT1B
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背景
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.,CKMT1B,CKMT,CKMT1,UMTCK,Signal Transduction,Kinase,CKMT1B
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分子量
- 47 kDa/50 kDa
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基因ID
- 1159
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UniProt
- P12532
抗原
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