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CKMT1B 抗体 (AA 1-85)

This anti-CKMT1B antibody is a 兔 多克隆 antibody detecting CKMT1B in WB, IP 和 IF. Suitable for 人.
产品编号 ABIN3017246
发货至: 中国

Quick Overview for CKMT1B 抗体 (AA 1-85) (ABIN3017246)

抗原

See all CKMT1B 抗体
CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

适用

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宿主

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克隆类型

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多克隆

标记

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This CKMT1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-85

    序列

    MAGPFSRLLS ARPGLRLLAL AGAGSLAAGF LLRPEPVRAA SERRRLYPPS AEYPDLRKHN NCMASHLTPA VYARLCDKTT PTGWT

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human CKMT1B (NP_066270.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

    别名

    CKMT1B

    背景

    Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.,CKMT1B,CKMT,CKMT1,UMTCK,Signal Transduction,Kinase,CKMT1B

    分子量

    47 kDa/50 kDa

    基因ID

    1159

    UniProt

    P12532
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