CHRNA10 抗体 (AA 25-240)
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北京 101111
Quick Overview for CHRNA10 抗体 (AA 25-240) (ABIN3017240)
抗原
See all CHRNA10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-240
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序列
- AEGRLALKLF RDLFANYTSA LRPVADTDQT LNVTLEVTLS QIIDMDERNQ VLTLYLWIRQ EWTDAYLRWD PNAYGGLDAI RIPSSLVWRP DIVLYNKADA QPPGSASTNV VLRHDGAVRW DAPAITRSSC RVDVAAFPFD AQHCGLTFGS WTHGGHQLDV RPRGAAASLA DFVENVEWRV LGMPARRRVL TYGCCSEPYP DVTFTLLLRR RAAAYV
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CHRNA10 (NP_065135.2).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:1000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
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别名
- CHRNA10
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背景
- Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.,CHRNA10,Signal Transduction,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNA10
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分子量
- 49 kDa
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基因ID
- 57053
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UniProt
- Q9GZZ6
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途径
- Sensory Perception of Sound, Synaptic Membrane
抗原
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