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Leptin Receptor 抗体

This anti-Leptin Receptor antibody is a 兔 多克隆 antibody detecting Leptin Receptor in WB 和 IF. Suitable for 人.
产品编号 ABIN3017146
发货至: 中国

Quick Overview for Leptin Receptor 抗体 (ABIN3017146)

抗原

See all Leptin Receptor (LEPR) 抗体
Leptin Receptor (LEPR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Leptin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide of human LEPR

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Leptin Receptor (LEPR)

    别名

    LEPR

    背景

    The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).,CD295,LEP-R,LEPRD,OB-R,OBR,LEPR,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,CD markers,Cardiovascular,Lipids,Fatty Acids,LEPR

    分子量

    96 kDa/102 kDa/103 kDa/109 kDa/132 kDa

    基因ID

    3953

    UniProt

    P48357

    途径

    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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