GRPR 抗体 (AA 235-384)
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北京 101111
Quick Overview for GRPR 抗体 (AA 235-384) (ABIN3017022)
抗原
See all GRPR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 235-384
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序列
- KNLIQSAYNL PVEGNIHVKK QIESRKRLAK TVLVFVGLFA FCWLPNHVIY LYRSYHYSEV DTSMLHFVTS ICARLLAFTN SCVNPFALYL LSKSFRKQFN TQLLCCQPGL IIRSHSTGRS TTCMTSLKST NPSVATFSLI NGNICHERYV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 235-384 of human GRPR (NP_005305.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
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别名
- GRPR
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背景
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.,GRPR,BB2,BB2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GRPR
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分子量
- 43 kDa
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基因ID
- 2925
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UniProt
- P30550
抗原
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