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GAD 抗体 (AA 1-200)

This anti-GAD antibody is a 兔 多克隆 antibody detecting GAD in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN3017019
发货至: 中国

Quick Overview for GAD 抗体 (AA 1-200) (ABIN3017019)

抗原

See all GAD (GAD1) 抗体
GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

适用

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宿主

  • 93
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克隆类型

  • 90
  • 45
多克隆

标记

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This GAD antibody is un-conjugated

应用范围

  • 93
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  • 25
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 24
    • 15
    • 11
    • 9
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    • 8
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    AA 1-200

    序列

    MASSTPSSSA TSSNAGADPN TTNLRPTTYD TWCGVAHGCT RKLGLKICGF LQRTNSLEEK SRLVSAFKER QSSKNLLSCE NSDRDARFRR TETDFSNLFA RDLLPAKNGE EQTVQFLLEV VDILLNYVRK TFDRSTKVLD FHHPHQLLEG MEGFNLELSD HPESLEQILV DCRDTLKYGV RTGHPRFFNQ LSTGLDIIGL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GAD67/GAD67/GAD1 (NP_000808.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

    别名

    GAD1

    背景

    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.,GAD1,CPSQ1,GAD,SCP,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Immunology & Inflammation,Neuroscience,GAD1

    分子量

    25 kDa/47 kDa/66 kDa

    基因ID

    2571

    UniProt

    Q99259
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