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DUSP1 抗体

This anti-DUSP1 antibody is a 兔 多克隆 antibody detecting DUSP1 in WB 和 IF. Suitable for 人.
产品编号 ABIN3016981
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DUSP1 抗体 (ABIN3016981)

抗原

See all DUSP1 抗体
DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This DUSP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide of human DUSP1 / MKP1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

    别名

    DUSP1

    背景

    The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.,DUSP1,CL100,HVH1,MKP-1,MKP1,PTPN10,Signal Transduction,Kinase,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,DUSP1

    分子量

    39 kDa

    基因ID

    1843

    UniProt

    P28562
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