EIF4G2 抗体 (AA 750-850)
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北京 101111
Quick Overview for EIF4G2 抗体 (AA 750-850) (ABIN3016941)
抗原
See all EIF4G2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 750-850
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序列
- IYKWIKDNIS PKLHVDKGFV NILMTSFLQY ISSEVNPPSD ETDSSSAPSK EQLEQEKQLL LSFKPVMQKF LHDHVDLQVS ALYALQVHCY NSNFPKGMLL R
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 750-850 of human EIF4G2 (NP_001409.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:1000,IHC,1:100 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
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别名
- EIF4G2
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背景
- Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.,EIF4G2,AAG1,DAP5,NAT1,P97,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,EIF4G2
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分子量
- 98 kDa/102 kDa
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基因ID
- 1982
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UniProt
- P78344
抗原
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