PGC
适用: 人
ELISA, IHC
宿主: 小鼠
Monoclonal
1G1H3
unconjugated
应用备注
WB,1:500 - 1:2000,IHC,1:100 - 1:200
限制
仅限研究用
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
PGC
(Pepsinogen C (PGC))
别名
PGC
背景
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.,PGC,PEPC,PGII,gastricsin,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PGC