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CNTF Receptor alpha 抗体 (AA 190-340)

This anti-CNTF Receptor alpha antibody is a 兔 多克隆 antibody detecting CNTF Receptor alpha in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3016492
发货至: 中国

Quick Overview for CNTF Receptor alpha 抗体 (AA 190-340) (ABIN3016492)

抗原

See all CNTF Receptor alpha (CNTFR) 抗体
CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

适用

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宿主

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克隆类型

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多克隆

标记

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This CNTF Receptor alpha antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 190-340

    序列

    NATAITFDEF TIVKPDPPEN VVARPVPSNP RRLEVTWQTP STWPDPESFP LKFFLRYRPL ILDQWQHVEL SDGTAHTITD AYAGKEYIIQ VAAKDNEIGT WSDWSVAAHA TPWTEEPRHL TTEAQAAETT TSTTSSLAPP PTTKICDPGE L

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 190-340 of human CNTFR (NP_001833.1).

    亚型

    IgG
  • 应用备注

    WB,1:400 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Yong, Groeger, von Bremen, Ruf: "Ciliary Neurotrophic Factor (CNTF) and Its Receptors Signal Regulate Cementoblasts Apoptosis through a Mechanism of ERK1/2 and Caspases Signaling." in: International journal of molecular sciences, Vol. 23, Issue 15, (2022) (PubMed).

  • 抗原

    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

    别名

    CNTFR

    背景

    This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.,CNTFR,Signal Transduction,Neuroscience,CNTFR

    分子量

    40 kDa

    基因ID

    1271

    UniProt

    P26992

    途径

    JAK/STAT Signaling, Feeding Behaviour
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