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HSPB8 抗体 (AA 1-196)

This anti-HSPB8 antibody is a 兔 多克隆 antibody detecting HSPB8 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN3016167
发货至: 中国

Quick Overview for HSPB8 抗体 (AA 1-196) (ABIN3016167)

抗原

See all HSPB8 抗体
HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

适用

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宿主

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克隆类型

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多克隆

标记

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This HSPB8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 21
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    AA 1-196

    序列

    MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW PGTLRSGMVP RGPTATARFG VPAEGRTPPP FPGEPWKVCV NVHSFKPEEL MVKTKDGYVE VSGKHEEKQQ EGGIVSKNFT KKIQLPAEVD PVTVFASLSP EGLLIIEAPQ VPPYSTFGES SFNNELPQDS QEVTCT

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-196 of human HSPB8/HSP22 (NP_055180.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

    别名

    HSPB8

    背景

    The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.,HSPB8,CMT2L,DHMN2,E2IG1,H11,HMN2,HMN2A,HSP22,Signal Transduction,Neuroscience,Neurodegenerative Diseases,HSPB8

    分子量

    21 kDa

    基因ID

    26353

    UniProt

    Q9UJY1
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