Mps1 抗体 (AA 517-856)
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北京 101111
Quick Overview for Mps1 抗体 (AA 517-856) (ABIN3016144)
抗原
See all Mps1 (TTK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 517-856
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序列
- ISVKGRIYSI LKQIGSGGSS KVFQVLNEKK QIYAIKYVNL EEADNQTLDS YRNEIAYLNK LQQHSDKIIR LYDYEITDQY IYMVMECGNI DLNSWLKKKK SIDPWERKSY WKNMLEAVHT IHQHGIVHSD LKPANFLIVD GMLKLIDFGI ANQMQPDTTS VVKDSQVGTV NYMPPEAIKD MSSSRENGKS KSKISPKSDV WSLGCILYYM TYGKTPFQQI INQISKLHAI IDPNHEIEFP DIPEKDLQDV LKCCLKRDPK QRISIPELLA HPYVQIQTHP VNQMAKGTTE EMKYVLGQLV GLNSPNSILK AAKTLYEHYS GGESHNSSSS KTFEKKRGKK
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 517-856 of human TTK (NP_001160163.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Mps1 (TTK)
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别名
- TTK
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背景
- This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.,TTK,CT96,ESK,MPH1,MPS1,MPS1L1,PYT,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centromere,TTK
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分子量
- 96 kDa/97 kDa
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基因ID
- 7272
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UniProt
- P33981
抗原
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