Histone H4 抗体 (2meArg3)
Quick Overview for Histone H4 抗体 (2meArg3) (ABIN3016060)
抗原
See all Histone H4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 2meArg3
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Methylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic methylated peptide corresponding to residues surrounding Arg3 of human histone H4
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation." in: Hepatology (Baltimore, Md.), Vol. 66, Issue 2, pp. 398-415, (2017) (PubMed).
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: "PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation." in: Hepatology (Baltimore, Md.), Vol. 66, Issue 2, pp. 398-415, (2017) (PubMed).
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- Histone H4
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背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy.,FO108,H4,H4/n,H4F2,H4FN,HIST2H4,Histone H4,HIST1H4A,HIST2H4A,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Histone H4
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分子量
- 11 kDa
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基因ID
- 8370
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UniProt
- P62805
抗原
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