PLVAP 抗体
(1 reference)Quick Overview for PLVAP 抗体 (ABIN298904)
抗原
See all PLVAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes murine plasmalemma vesicle-associated protein (PLVAP), a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumor angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.
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纯化方法
- Affinity purified
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免疫原
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Type of Immunogen: Native protein -
亚型
- IgG2a
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anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 123-393) antibody
PLVAP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 51-150) antibodyPLVAP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 203-442) antibodyPLVAP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 63-442) antibodyPLVAP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 214-242) antibodyPLVAP 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB17891 unconjugated
anti-Plasmalemma Vesicle Associated Protein (PLVAP) (AA 221-250), (Middle Region) antibodyPLVAP 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Approved: Flo, IHC, IHC-Fr (1:25 - 1:100)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. -
说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze thaw cycles. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
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: "Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta." in: PLoS ONE, Vol. 9, Issue 11, pp. e111762, (2015) (PubMed).
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: "Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta." in: PLoS ONE, Vol. 9, Issue 11, pp. e111762, (2015) (PubMed).
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- PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
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别名
- PV1 / PLVAP
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背景
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Name/Gene ID: PLVAP
Synonyms: PLVAP, gp68, FELS, Plasmalemma vesicle protein 1, PV-1, PV1 -
基因ID
- 83483
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UniProt
- Q9BX97
抗原
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