TACR3 抗体
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北京 101111
Quick Overview for TACR3 抗体 (ABIN298071)
抗原
See all TACR3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human TACR3 otherwise known as NK3 Receptor (NK3R), a 52.2 kD multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. TACR3 is a receptor for the tachykinin neuropeptide, neuromedin-k otherwise known as neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system, and it is likely that these signals lead to the release of vasopressin and oxytocin into the circulation. Studies with mice indicate that TACR3 is involved in learning and memory. AHP1492 does not recognize NK1R or NK2R.
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纯化方法
- Affinity purified
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免疫原
- An 18 amino acid peptide from near the center of human TACR3.
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应用备注
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Approved: IHC, IHC-P (5 μg/mL), WB (0.5 - 1 μg/mL)
Usage: Western Blot: LS-C56946 detects a band of approximately 46kD in RAW264.7 cell lysates. Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Short term: -20°C
Long term: -20°C.
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- TACR3 (Tachykinin Receptor 3 (TACR3))
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别名
- TACR3 / NK3R
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背景
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Name/Gene ID: TACR3
Subfamily: Tachykinin
Family: GPCR
Synonyms: TACR3, HH11, Nmk-r, NK3R, NKR, Tachykinin receptor 3, Neurokinin B, Neurokinin B receptor, NK-3 receptor, NK-3R, TAC3R, Neurokinin 3 receptor, Neurokinin beta receptor, Neuromedin-K receptor, TAC3RL -
基因ID
- 6870
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UniProt
- P29371
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途径
- Feeding Behaviour
抗原
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