CXCR4 抗体
Our Local Distributor
北京 101111
Quick Overview for CXCR4 抗体 (ABIN2967165)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-Hu CD184 Purified
-
特异性
- The mouse monoclonal antibody 12G5 recognizes an extracellular epitope of CD184, a 45 kDa G-protein-linked CXC chemokine receptor widely expressed on blood and tissue cells.
-
交叉反应 (详细)
- Human, Non-Human Primates
-
纯化方法
- Purified by protein-A affinity chromatography.
-
纯度
- > 95 % (by SDS-PAGE)
-
免疫原
- CP-MAC-infected Sup-T1 cells
-
亚型
- IgG2a kappa
-
-
-
-
应用备注
- Flow cytometry: Recommended dilution: 2-4 μg/mL.
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store at 2-8°C. Do not freeze.
-
-
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
-
别名
- CD184
-
背景
- C-X-C motif chemokine receptor 4,CD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.,CXCR4, LAP3, LCR1, HM89, fusin, SDF1R
-
基因ID
- 7852
-
UniProt
- P61073
-
途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
-