LACTB 抗体
Our Local Distributor
北京 101111
Quick Overview for LACTB 抗体 (ABIN2962025)
抗原
See all LACTB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Reacts withType IV betalactamase of Enterobacter cloacae.
-
纯化方法
- Purified
-
免疫原
- Type IV beta lactamase from Enterobacter cloacae, accession no. P05364.
-
亚型
- IgG3
-
-
-
-
应用备注
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ELISA10 - 20 μg/mL (optimized for beta-lactamase on solid phase at 10 μg/mL). -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS, pH 7.4
-
注意事项
- Dilute in PBS or medium that is identical to that used in the assay system.
-
储存条件
- -20 °C
-
储存方法
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
-
有效期
- 12 months
-
-
- LACTB (Lactamase, beta (LACTB))
-
别名
- beta-Lactamase
-
背景
-
The beta-lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta-lactams are structurally related through the presence of a core beta-lactam ring. Bacterial resistance to beta-lactams continues to increase, primarily due to microbial production of beta-lactamases. Beta-lactamases catalyze the hydrolysis of the beta-lactam bond which destroys anti-bacterial activity. Bacteria the produce TEM- or SHV-type beta-lactamases have point mutations in structural genes that have extended the substrate specificity of these betalactamases. As a result, many of the beta-lactamase-producing Gram-negative bacteria have become multi-drug resistant. Beta-lactamase from Enterobacter cloacae is a serine beta-lactamase with substrate specificity for cephalosporins.
Beta-lactamase Cephalosporinase Gene nam: ampC E. cloacae -
UniProt
- P05364
抗原
-