LACTB
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 555
应用备注
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only: ELISA10 - 20 μg/mL (optimized for beta-lactamase on solid phase at 10 μg/mL).
限制
仅限研究用
缓冲液
PBS, pH 7.4
注意事项
Dilute in PBS or medium that is identical to that used in the assay system.
储存条件
-20 °C
储存方法
Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
有效期
12 months
抗原
LACTB
(Lactamase, beta (LACTB))
别名
beta-Lactamase
背景
The beta-lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta-lactams are structurally related through the presence of a core beta-lactam ring. Bacterial resistance to beta-lactams continues to increase, primarily due to microbial production of beta-lactamases. Beta-lactamases catalyze the hydrolysis of the beta-lactam bond which destroys anti-bacterial activity. Bacteria the produce TEM- or SHV-type beta-lactamases have point mutations in structural genes that have extended the substrate specificity of these betalactamases. As a result, many of the beta-lactamase-producing Gram-negative bacteria have become multi-drug resistant. Beta-lactamase from Enterobacter cloacae is a serine beta-lactamase with substrate specificity for cephalosporins.
Beta-lactamase Cephalosporinase Gene nam: ampC E. cloacae