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Abeta 1-40 抗体

This anti-Abeta 1-40 antibody is a 小鼠 单克隆 antibody detecting Abeta 1-40 in IHC, WB, IP, ELISA 和 IF. Suitable for 小鼠 和 人.
产品编号 ABIN2961827
发货至: 中国

Quick Overview for Abeta 1-40 抗体 (ABIN2961827)

抗原

See all Abeta 1-40 抗体
Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

适用

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小鼠, 人

宿主

  • 17
  • 1
小鼠

克隆类型

  • 17
  • 1
单克隆

标记

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This Abeta 1-40 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

克隆位点

Ab40-1
  • 特异性

    Reacts with human and mouse Aβx-40

    纯化方法

    Purified

    免疫原

    Synthetic peptide corresponding to Abeta35-40.

    亚型

    IgG1
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    1 - 10 μg/mL for any application

    限制

    仅限研究用
  • 缓冲液

    PBS pH 7.4

    注意事项

    Dilute in PBS or medium which is identical to that used in the assay system.

    储存条件

    -20 °C

    储存方法

    Stable for at least one year at -20°C

    有效期

    12 months
  • 抗原

    Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

    别名

    Amyloid beta 1-40

    背景

    Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Aβ (Aβ42) and amino-terminally truncated forms of Aβ (Aβx-42) are the predominant species of Aβ typically found in diffuse and senile plaques within the AD brain. There is a strong correlation between Aβ40 positivity and mature plaques. In the AD cortex, diffuse plaques, representing the earliest stage of Aβ deposition, are positive for Aβ42, but negative for Aβ40.

    Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Beta-amyloid protein 40 Beta-APP40 Gene name: APP, A4, AD1

    基因ID

    351

    UniProt

    P05067
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